Carotid Sinus Reflex Control of Coronary Blood Flow

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Carotid Sinus Reflex Control of Coronary Blood Flow

The role of the carotid sinus reflex in control of the blood flow in the left circumflex coronary artery was studied in nine open-chest dogs anesthetized with chloralose. Flow was measured with an electromagnetic flowmeter. The effects of bilateral common carotid occlusion were examined in a three-part experiment in each dog. (1) Under vagotomy (control) conditions, occlusion of both common car...

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Carotid sinus reflex control of coronary blood flow in human subjects.

Systemic and coronary hemodynamics were assessed before and during a reduction in carotid transmural pressure. This reduction was induced by means of a pneumatic neck chamber in 15 normal subjects and 15 hypertensive patients with a normal coronary arteriogram. A reduced baroreflex responsiveness was demonstrated in hypertensive patients as compared with normal subjects by evaluating both the r...

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Carotid sinus baroreceptor reflex control of respiration.

We have studied the effect of the carotid sinus baroreceptor reflex on respiration in 10 vagotomized, spontaneously breathing, pentobarbital anesthetized dogs. The carotid body chemoreceptor reflex response was eliminated by surgically excluding the carotid bodies from the carotid sinus baroreceptor area. Steady state frequency, tidal volume, and minute ventilation were measured after 25 mm Hg ...

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Hypersensitive Carotid Sinus Reflex

A patient with transient, intermittent, complete heart block had periods of asystole, accompanied by syncope, whenever his cardiac rhythm shifted spontaneously from regular sinus rhythm to complete auriculoventricular dissociation. Similar clinical and electrocardiographic findings were produced by carotid sinus pressure when there was regular sinus rhythm. During the periods of heart block car...

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Measurement of Coronary Sinus Blood Flow

In 14 subjects with normal coronary arteries the mean coronary sinus blood flow was 122 25 mI/min (range, 83 to 159 ml/min). The blood flow computed per 100 g of left ventricle was 82 + 16 ml/min, which is in the range of values obtained by nitrous oxide and coincidence counting methods. In 35 patients with arteriographically confirmed coronary artery disease the mean flow was similar (128 + 20...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1968

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.23.2.223